One of the biggest changes we have made on the new UniProt website is to improve your
usage of the tools associated with our data - BLAST, Align, ID mapping and Peptide
You can easily access all of these from the homepage of the new website,
or from the toolbar of any entry.
When you open BLAST, you can search by on any UniProtKB ID (e.g. P05067 or
A4_HUMAN) or a UniParc protein sequence archive ID (e.g. UPI0000000001) to
autofill the protein sequence. One of the biggest changes we have made is to allow
you to select the species you wish to BLAST against, so if you are only interested in
dog (TaxID:9615), start to type the common (dog) or species (Canis lupus familiaris)
name and the autocomplete will help you select the correct taxonomic group
(TaxID:9615), to search for a match. You can choose to limit your search to any
level of the taxonomic tree, so you can search your dog sequence against, for example,
all mammalian sequences by using the appropriate taxonomic identifier (TaxID:40674).
You can also upload a list of sequences to BLAST, up to a maximum of 20, from an
external file. You can reset the BLAST parameters, should you wish, and name your
job so you can easily identify when you return in up to a week's time.
Once your job has run,, it will appear in the new Tool Results view. Here you can see
all of your jobs that have completed over the last 7 days, identified by the names you
have chosen to give them.
When you open your job, we have increased the number of ways you can view the results.
For example, in the case of a Sequence Alignment, you can take a look at the traditional
view of the aligned amino acids, with a summary of any one of the entries you select acting
as a reference sequence below, or you can see a phylogenetic view or a percent identity
Loading data from a file (up to a maximum of 100 sequences) and restricting the search
criteria by species are features also available in the Peptide Search tool, where users,
for example proteomics scientists, can match peptide to protein, and an increasing
number of database identifiers are now available in the ID mapping tool for users to
We hope you find this first look at the new beta version of the UniProt website useful,
and easy to navigate. Please let us know if you have any problems at all, or if you can
think of any way in which it can be further improved by using the contact form accessible
from every page.